NUTRIGENOMICS AND PERSONALIZED NUTRITION: BRIDGING GENETIC INSIGHTS WITH PUBLIC HEALTH INTERVENTIONS

Authors

  • Fitri Dian Nila Sari Universitas Nahdlatul Ulama Sumatera Utara, Indonesia Author

Keywords:

nutrigenomics, personalized nutrition, genetics, public health, nutrition interventions

Abstract

This study aims to explore the role of nutrigenomics and personalized nutrition in the context of public health interventions through a literature review approach. Nutrigenomics is a branch of science that studies the interaction between genes and nutrients, and how individual genetic variations influence responses to certain food intakes. In recent decades, the development of genomic technologies has enabled a deeper understanding of how nutrition can be tailored to an individual's genetic profile to prevent disease and promote optimal health. Through a systematic review of various scientific publications, articles, and recent research reports, this study identifies the potential for integrating nutrigenomics into community nutrition strategies, while analyzing the ethical, social, and practical challenges in its implementation. The results of the study indicate that personalized nutrition based on genetic data has great prospects in improving the effectiveness of public health programs, especially in efforts to prevent non-communicable diseases such as diabetes, obesity, and cardiovascular disease. However, the widespread implementation of this approach still requires a strong regulatory framework, public education, and multidisciplinary collaboration between nutritionists, geneticists, and policy makers. This study is expected to be the basis for the development of scientific evidence-based nutrition policies and more precise approaches in the future.

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References

Adams, S. H., Anthony, J. C., Carvajal, R., Chae, L., Khoo, C. S. H., Latulippe, M. E., Matusheski, N. V., McClung, H. L., Rozga, M., Schmid, C. H., Wopereis, S., & Yan, W. (2020). Perspective: Guiding Principles for the Implementation of Personalized Nutrition Approaches That Benefit Health and Function. Advances in Nutrition, 11(1), 25–34. https://doi.org/10.1093/advances/nmz086

Agostoni, C., Boccia, S., Banni, S., Mannucci, P. M., & Astrup, A. (2021a). Sustainable and personalized nutrition: From earth health to public health. European Journal of Internal Medicine, 86, 12–16. https://doi.org/10.1016/j.ejim.2021.02.012

Agostoni, C., Boccia, S., Banni, S., Mannucci, P. M., & Astrup, A. (2021b). Sustainable and personalized nutrition: From earth health to public health. European Journal of Internal Medicine, 86, 12–16. https://doi.org/10.1016/j.ejim.2021.02.012

Agrawal, P., Kaur, J., Singh, J., Rasane, P., Sharma, K., Bhadariya, V., Kaur, S., & Kumar, V. (2024). Genetics, Nutrition, and Health: A New Frontier in Disease Prevention. Journal of the American Nutrition Association, 43(4), 326–338. https://doi.org/10.1080/27697061.2023.2284997

Bahinipati, J., Sarangi, R., Mishra, S., & Mahapatra, S. (2021). Nutrigenetics and nutrigenomics: A brief review with future prospects. Biomedicine, 41(4), 714–719. https://doi.org/10.51248/.v41i4.445

Clemente-Suárez, V. J., Peris-Ramos, H. C., Redondo-Flórez, L., Beltrán-Velasco, A. I., Martín-Rodríguez, A., David-Fernandez, S., Yáñez-Sepúlveda, R., & Tornero-Aguilera, J. F. (2024). Personalizing Nutrition Strategies: Bridging Research and Public Health. Journal of Personalized Medicine, 14(3), Article 3. https://doi.org/10.3390/jpm14030305

Fischer, F. (2024a). The Interplay of Nutrition, Genetics, and Lifestyle in the Prevention and Management of Chronic Diseases: Insights from Modern Research. Public Health Spectrum, 1(1). https://docentra.com/nutritionchronicdiseases

Fischer, F. (2024b). The Interplay of Nutrition, Genetics, and Lifestyle in the Prevention and Management of Chronic Diseases: Insights from Modern Research. Public Health Spectrum, 1(1). https://docentra.com/nutritionchronicdiseases

Hosseiniara, S. M., & Hosseini Zijoud, S. S. (2024). Nutrigenomics: A promising frontier in chronic disease prevention. Journal of Preventive and Complementary Medicine, 3(4), 195–200. https://doi.org/10.22034/jpcm.2024.496108.1196

Kapellou, A., Salata, E., Vrachnos, D. M., Papailia, S., & Vittas, S. (2025). Gene–Diet Interactions in Diabetes Mellitus: Current Insights and the Potential of Personalized Nutrition. Genes, 16(5), 578. https://doi.org/10.3390/genes16050578

Khoury, M. J. (2010). From Genes to Public Health: The Applications of Genetic Technology in Disease Prevention. In The Ethics of Public Health, Volumes I and II. Routledge.

Lagoumintzis, G., & Patrinos, G. P. (2023). Triangulating nutrigenomics, metabolomics and microbiomics toward personalized nutrition and healthy living. Human Genomics, 17(1), 109. https://doi.org/10.1186/s40246-023-00561-w

Lasky-Su, J. (2017). Chapter 19—Statistical Techniques for Genetic Analysis. In D. Robertson & G. H. Williams (Eds.), Clinical and Translational Science (Second Edition) (pp. 347–362). Academic Press. https://doi.org/10.1016/B978-0-12-802101-9.00019-3

Lucini, L., Marti-Quijal, F. J., Barba, F. J., Rocchetti, G., Quilez, F., Cuesta, L., Denoya, G. I., Vieira, P., Pinto, C. A., & Saraiva, J. A. (2020). Chapter 9—Nutrigenomics and public health. In F. J. Barba, P. Putnik, & D. B. Kovačević (Eds.), Agri-Food Industry Strategies for Healthy Diets and Sustainability (pp. 219–233). Academic Press. https://doi.org/10.1016/B978-0-12-817226-1.00009-6

Mills, M. C., Barban, N., & Tropf, F. C. (2020). An Introduction to Statistical Genetic Data Analysis. MIT Press.

Mishra, U. N., Jena, D., Sahu, C., Devi, R., Kumar, R., Jena, R., Irondi, E. A., Rout, S., Tiwari, R. K., Lal, M. K., Baig, M. J., & Kumar, A. (2022). Nutrigenomics: An inimitable interaction amid genomics, nutrition and health. Innovative Food Science & Emerging Technologies, 82, 103196. https://doi.org/10.1016/j.ifset.2022.103196

Mozsik, G., & Díaz-Soto, G. (2021). Mineral Deficiencies: Electrolyte Disturbances, Genes, Diet and Disease Interface. BoD – Books on Demand.

Paving the way to better population health through personalised nutrition—Mathers—2019—EFSA Journal—Wiley Online Library. (n.d.). Retrieved July 2, 2025, from https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2019.e170713

Reddy, V. S., Palika, R., Ismail, A., Pullakhandam, R., & Reddy, G. B. (2018). Nutrigenomics: Opportunities & challenges for public health nutrition. Indian Journal of Medical Research, 148(5), 632. https://doi.org/10.4103/ijmr.IJMR_1738_18

Verma, M., Hontecillas, R., Tubau-Juni, N., Abedi, V., & Bassaganya-Riera, J. (2018). Challenges in Personalized Nutrition and Health. Frontiers in Nutrition, 5. https://doi.org/10.3389/fnut.2018.00117

Vyas, S. (2022a). Advances in Nutrigenomics and Applications in Public Health: A Recent Update. Current Research in Nutrition and Food Science Journal, 10(3), 1092–1104.

Vyas, S. (2022b). Advances in Nutrigenomics and Applications in Public Health: A Recent Update. Current Research in Nutrition and Food Science Journal, 10(3), 1092–1104.

Wuni, R., & Vimaleswaran, K. S. (2024). Barriers in Translating Existing Nutrigenetics Insights to Precision Nutrition for Cardiometabolic Health in Ethnically Diverse Populations. Lifestyle Genomics, 17(1), 122–135. https://doi.org/10.1159/000541909

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Published

2025-07-02

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